Colchicine Generic 1 mg 30 Tabs

In stock
$5.95
0 reviews

Colchicine: instructions for use 

Colchicine is a substance of alkaloid nature, which significantly reduces the movement of leukocytes to the focus of the inflammatory process. This inhibits the uptake of microcrystalline parts of uric acid by phagocytes. 

Colchicine, which affects uric acid metabolism, is produced on a plant basis. The active ingredient of the same name in the remedy is isolated from the great flintless. This herbaceous plant has long been used in folk medicine to reduce joint pain and prevent the progression of inflammation.

The medicine is produced in tablet form. Tablets are mostly white, but sometimes have a slightly yellowish tinge. Round biconvex tablets have a risk, which simplifies compliance with the prescribed dosage. 

The drug has analgesic and anti-inflammatory effects. After taking it, it is possible to quickly stop an acute attack of gout. In addition, the active ingredient delays the deposition of uric acid microcrystals in the tissues. 

Colchicine Generic is able to significantly inhibit cell division, stops miosis, stops degranulation processes in neutrophils. 

The drug stops the development of amyloidosis and reduces the intensity of formation of amyloid structure fibrils. Colchicine tablets are highly effective in terms of stopping and preventing gout attacks of an acute nature. The therapeutic effect develops during the first day of use (in 75% of patients).

Indications for use

Colchicine is prescribed for:

1. In the treatment of gout. This disease is characterized by acute joint pain on the background of impaired uric acid metabolism and urate deposition in tissues. The remedy is shown to relieve pain at exacerbation of the disease and to slow its progression.

2. Amyloidosis, when a complex protein-polysaccharide compound - amyloid - is deposited in the tissues. This leads to malfunction of almost all systems and organs in the body.

3. Inflammatory diseases in otorhinolaryngology and dentistry.

4. Mediterranean fever, which is a hereditary disease associated with amyloid deposition in tissues. The main symptom is recurrent sudden increase in body temperature and severe chills.

5. Phlebitis. In this case, there is inflammation of the venous wall on the background of pathologies of infectious and inflammatory nature.

6. Scleroderma. The disease is characterized by the appearance of scar tissue on the skin and internal organs.

7. Chondrocalcinosis. When this pathology occurs, calcium pyrophosphate crystals are deposited in the articular cartilage and sac, causing painful sensations.

Treatment is prescribed by a doctor, so Colchicine over the counter is not dispensed. If you do not have time to make an appointment with a doctor, and treatment cannot be interrupted, you can buy Colchicine otc, as the doctor who works for the pharmacy will write a prescription for you. 

Foods to avoid when taking Colchicine

A diet low in purines can not only prevent the symptoms of diseases associated with elevated levels of uric acid in the blood but also improve overall health and well-being.

Purines are organic compounds that are part of nucleic acids and other important biologically active substances. In the human body, the end product of purine metabolism is uric acid. Disorders of purine metabolism can lead to increased levels of uric acid in the blood - hyperuricemia.

A diet low in purines can not only prevent the symptoms of diseases associated with elevated levels of uric acid in the blood but also improve overall health and well-being.

Gout patients should avoid excessive intake of alcoholic beverages, especially beer. Moderate consumption of wine is not associated with gout exacerbation. Excessive alcohol consumption leads to more frequent gout relapses, even with allopurinol therapy.

Patients should avoid drinks sweetened with high fructose syrup. It is also important to limit natural sweet fruit juices, table sugar, sugary drinks and desserts, and table salt. Grapefruit and grapefruit juice should be avoided when treated with Colchicine.

Foods containing high levels of purines include:

  • red meat and game;
  • certain seafood including: tuna, sardines, anchovies, herring, mussels, cod, scallops, trout, and haddock;
  • meat by-products (kidney, liver, heart, etc.)
  • legumes (peas, lentils, etc.).

It is recommended that these foods be significantly limited or avoided:

  1. High-fat foods.
  2. Alcohol. Beer and whiskey are particularly high in purines. Alcohol also causes dehydration, which makes it difficult for the body to eliminate uric acid.
  3. Sweetened beverages: Fructose is an ingredient in many sweetened beverages, including fruit juices and carbonated drinks, and its excessive consumption is accompanied by a risk of developing gout.

Maintaining a high level of hydration by drinking plenty of fluids can be helpful in preventing gout recurrence. Since the association of gout with the development of atherosclerosis is well known, a diet low in cholesterol and fat is advisable.

Meals for gout should be fractional, the number of meals a day - from 4 to 6, portions of small volume. It is strongly not recommended to use salt in gout, if there is no way to abandon it, its quantity should be reduced. The basis of the diet in gout is lean fish and meat, which are cooked in boiled or baked form, vegetables and fruits. It is obligatory to consume dairy products every day.

Weight loss in obese patients can reduce uric acid levels. However, diets that cause ketosis (such as starvation) should be avoided.

How to take Colchicine for acute gout?

There is a regimen for taking to relieve acute pain. To do this, a whole tablet is taken. Then you take another 0.5-1 tablets at an interval of 60-120 minutes. The treatment is continued until the pain syndrome is relieved. The maximum allowable dose is 8 tablets per day.

How to use the drug?

It starts with a single dose, which is 1 mg. Then the drug is taken 0.5 mg every 3 hours until the intensity of painful signs is reduced. The total allowable amount of the drug in 1 course is 6 mg, exceeding the maximum dosage is strictly forbidden. The repeated course of treatment can be carried out not earlier than after 3 days. Reception for the prevention of relapses is 0.5 mg 2 to 3 times a day.

Elderly patients, people with kidney and liver diseases may need to reduce the dose or reduce the frequency of administration of the drug. The duration of the therapeutic course is determined by the doctor depending on the severity and intensity of symptoms, but most often it is short with high doses of the drug and frequent administration.

When to take Colchicine?

It is important to follow the doctor's recommendations. Most often, the drug is prescribed in the evening.

How long does it take for Colchicine to work?

Colchicine is rapidly and intensively absorbed from the gastrointestinal tract. The average maximum plasma concentration is 4.2 ng/ml and is reached approximately 70 minutes after a dose of 1 mg.

How long does Colchicine stay in your system?

The elimination half-life is 9.3 hours.

Why does Colchicine cause diarrhea?

The reason Colchicine causes diarrhea is to damage the mucosa of the small and large intestines. 

What are the side effects of Colchicine?

Colchicine use may be accompanied by: 

  • malabsorption syndrome;
  • peripheral neuritis;
  • nausea;
  • crust-like rash;
  • neuropathy;
  • azoospermia;
  • renal dysfunction;
  • vomiting;
  • leukopenia;
  • myelosuppression;
  • diarrhea;
  • urticaria;
  • depression;
  • thrombocytopenia;
  • anorexia;
  • myopathy;
  • aplastic anemia;
  • epigastric pain;
  • neutropenia;
  • alopecia of a temporary nature;
  • liver dysfunction;
  • agranulocytosis.

 Before Colchicine buy, consult your physician and read the instructions for the drug.

Contraindications

Colchicine is not prescribed in:

  • hepatic insufficiency of an acute nature;
  • bone marrow dysfunction;
  • serious gastrointestinal disorders;
  • neutropenia;
  • indications in gerontological patients;
  • renal failure of an acute nature;
  • alcoholism;
  • serious diseases of the myocardial and vascular system;
  • infections of a purulent nature;
  • indications in pregnant women;
  • hypersensitivity reactions to colchicine and its analogues. 

The drug is prescribed only by a physician, self-treatment can only aggravate the disease.

Pregnancy

Prescribing is possible only under strict medical supervision in the absence of a safer alternative and in the presence of clear indications. The benefits of using the therapeutic agent must outweigh the possible high risks to the fetus. 

What happens if you take too much Colchicine?

Exceeding the therapeutic doses of the drug is accompanied by: 

  • diarrhea of a severe nature;
  • hematuria;
  • hemorrhagic gastroenteritis;
  • oral pain;
  • hypotension;
  • seizures;
  • bouts of vomiting;
  • pulmonary infiltrates;
  • burning of the skin;
  • epigastric pain;
  • severe dehydration;
  • altered myocardial function with ST-segment elevation;
  • bouts of nausea;
  • oliguria;
  • respiratory depression;
  • acute renal failure;
  • hypovolemic shock;
  • decreased myocardial contractility;
  • hepatocellular damage;
  • ascending paralysis. 

The patient should be treated in a toxicology inpatient unit. Hemodialysis in colchicine overdose is not used due to ineffectiveness. There is no specific antidote to colchicine. 

Colchicine drug interactions

It is important to tell your doctor what drugs you are taking besides Colchicine because some of them are incompatible. Examples are shown in the table below. 

Pharmacological group

Possible result of interaction with Colchicine

Sympathomimetics

Sympathomimetic potentiation

Cyanocobalamin

Impairment of absorption of cyanocobalamin

NSAIDS

Increased likelihood of thrombocytopenia, decreased white blood cell count

Cyclosporine

Risk of myopathic changes

Cytostatics

Decrease of Colchicine effectiveness

Drugs that alkalize the urine

Potentiation of the effects of Colchicine

 To buy generic Colchicine online, go to the website of our online pharmacy. You can buy Colchicine online from the comfort of your home, patients are always available the price of the drug and information about availability. 

Reviews Colchicine Generic 1 mg 30 Tabs

Leave your review

These are the payment methods available:

  • Money Transfer ( Money Gram or Western Union)
  • Bitcoin
  • Paypal
  • Bank Wire

 

Shipping & Returns

 we are a Registered and Licensed Mexican pharmacy we assure you top quality medicines without the worry of your health care provider, employer or any other group finding out what rightfully is a private issue.

Did you know that your private medical file can be used against you to raise your insurance rates or in some cases and countries to lose your job? We take your privacy very seriously and by using these payment methods and the way in which we use them your bank does not directly get charged from our pharmacy. This way your medical needs stay as private as possible.

You will also receive a complete invoice in your email with payment totals and simple payment instructions toward the bottom of the email should you wish to pay at a later convenience.

IMPORTANT: If you need to make some changes in regards an existing order, contact us within 24 hours, otherwise, Medicines Mexico is not liable due to errors on customer’s information or products presentation. 

 

Shipping Methods.

To ensure the delivery of your order we handle EXPRESS SHIPPING only. Signature is required.
Tracking numbers for all orders will be sent with instructions once shipped.

 

How long does it take to ship the drugs to my home or office?

  • Express USA time frame: 10-21 business days.   ($24.95 USD Signature required)
  • Express World Wide time frame: 15-30 business days.  ($39.95 USD Signature required)

 

*Due to unexpected Postal Service changes, one of the shipping methods above could be temporarily disabled.
 

IMPORTANT: Please ensure your mail program is configured to accept email from www.mexicanrxpharm.com sender, add our email to your non blocked email address so we may send invoices, order status and shipping confirmations. If you do not receive your invoice immediately after this, please check your spam filter and make necessary changes. 

We reply promptly to your enquiries and requests emails, but are too busy to repeatedly resend email that customers do not receive because our replies have been moved to a customers’ Spam, Junk or Bulk email folder.

Online pharmacy Medicines Mexico shipping terms and conditions.
Our team endeavors to process all orders and ship within 72 business hours. All credit card and electronic check payments for your mexicanrxpharm take 24 to 48 hours to be approved by our Payment Processor; upon verification your order will be processed. If there are any problems with your order, we will contact you, so please ensure the email address and phone number you provide is correct, and that any spam filtering software you use accepts email from www.mexicanrxpharm.com

Express Shipping.
We offer Mex Post Express Shipping as an option. This option costs from $24.95 depending on the quantity of medications in your order (up to 9 medications). This option requires a customer signature on delivery. For all other locations Express Shipping is $39.95. All packages are shipped in plain packaging to guarantee your privacy. All packages are sent by parcel express mail from Mexico. Some parcels require a signature upon delivery at our discretion. There are no other handling fees, drug dispensing fees, or Mexican customs charges. If two or more people are ordering their prescription drugs from the same address at the same time, you will be billed for only one shipping charge from our Mexico pharmacy, up to our maximum order quantities limited by customs to 90 day supply. We are able to provide a tracking number on your express shipping parcels. If after 30 business days your order has not arrived, first check with your local postal office to ensure that your package is not being held for pick-up. If you still have problems, please contact us by email and we will attempt to assist you.

Notice Left
If no one is at home at the time of delivery, the status of you order on the Postal System will be updated to “Notice Left” which means USPS attempted to deliver your item and a notice was left because an authorized recipient was not available. You may arrange redelivery by visiting or calling 800-ASK-USPS, or may pick up the item at the Post Office indicated on the notice. If this item is unclaimed after five days then it will be returned to the sender. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).

Holidays
Note that on Holidays season, the Mexican Postal, USA and other countries will be extra busy; therefore a delay is expected in packages shipped during this season. You will need to consider as well the Mexican holidays. We appreciate your understanding, our customer service will be happy to assist you and available to inform you the latest status on your existing order shipped, you can always contact us at Toll Free number or email address.

Order Cancellation
Due to our policy of same day payment processing, ORDERS CANNOT BE CANCELLED.

Returns
Due to government regulations and the possibility of tampering with medications, returns cannot be accepted. In case your package is returned due to no one was available to sign for it. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).

How to find the online pharmacy drug you need.
There are many more medications available in Mexico that are not listed on our website. If you can’t find the Mexican drug or medication you require, please contact us and we may be able to help. Some products are listed only in a single dosage size or medicine type, but may be available in other dosages and forms. Our experienced Mexican pharmacy Pharmacists will do their best to accommodate your requirements. Please always specify the chemical name of the medication (and any applicable brand name) with all inquiries. Please feel free to ask about ANY drug. We will reply promptly to your request.

What you should know about brand and generic drug alternates.
Prescription drugs are a costly medical expense, especially for the elderly, those who are chronically ill and those with no or minimal drug coverage on their Health Insurance. However, each state in America has a law that allows pharmacists to substitute less expensive generic drugs for many brand name products. Depending on your prescription needs, your savings could be very significant. Before you talk with your doctor or pharmacist about switching, there are things you should know about generic drugs.

What is the difference between a generic and brand name drug?
Nothing except for the name, packaging, and the price, a generic drug is called by its chemical name; manufacturers assign their own brand name. The generic products have the same ingredients. Standard practice and most state laws require that a generic drug be generically equivalent to its brand name counterpart. That is, it must have the same active ingredients, strength, and dosage form, be it a pill, liquid, or injection. The generic drug also must be therapeutically equivalent. It must be the same drug chemically and have the same medical effect.

Do all drugs have generic equivalents?
No. Some drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.

Will my doctor automatically prescribe generic drugs?
It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate or to define the chemical name for the prescription. This will ensure you are purchasing the correct Mexico drug. Generic products will be as effective and less costly. Or, you can order only brand name products if you wish. www.mexicanrxpharm.com Mexico pharmacy offers a wide selection of both Brand Name & Generic Mexico medicine. Our Mexican generic drugs are of the highest quality, selected only from the most reputable manufacturers, and are safe to replace brand name medications costing much more.

 


TOLL FREE:
info@mexicanrxpharm.com

Feel free to contact us for further information.
Click on continue to return to the Home Page.

Colchicine Generic 1 mg 30 Tabs
In stock

$5.95

Colchicine Generic 1 mg 30 Tabs