Clonazepam has a sedative and mild sedative effect. This is due to the effect of the active components on the reticular formation of the brain stem and nonspecific thalamic nuclei. The sedative (soporific) effect is manifested by a reduction of neurotic symptoms (in particular - fear and anxiety).
The drug has a bioavailability of over 90% when taken orally. The duration of action of Clonazepam in adults is 10-12 hours. In children, the drug stays in the body for 6-8 hours.
The half-life of the drug in the body varies from 18 to 20 hours. It’s eliminated largely with the urine.
Clonazepam is an anticonvulsant drug. Lorazepam is an anxiolytic (anti-anxiety drug).
Clonazepam is taken orally only. Lorazepam is taken intravenously, intramuscularly, and sublingually. Clonazepam is a long-acting benzodiazepine with a rapid onset (1-4 hours). Lorazepam is a short-acting benzodiazepine. The half-life of this drug is 15 hours.
Clonazepam remains in the urine for 18-20 hours. When this medication has been taken as a sleeping pill (for frequent awakenings, restless sleep, and other types of insomnia), there is little residual effect during the first half of the day.
Clonazepam may be taken in men 18 hours before and 8 hours after drinking alcoholic beverages. Women may take the drug the day before they are supposed to take alcohol and 14 hours after taking it. Clonazepam and alcohol must not be taken at the same time as it reduces blood pressure, leads to palpitations and in some cases may cause epileptic seizures.
Clonazepam is an intermediate-acting drug. Xanax is a short-acting drug. On average, the half-life of Xanax is 6-12 hours. The greatest efficacy of Xanax is observed within 1 to 2 hours after ingestion. Clonazepam's greatest efficacy occurs within 4 hours.
Xanax's shorter half-life is associated with the rapid development of drug tolerance. If a person takes the drug for a very long time, a steady increase in dosage is required over time to achieve an effect.
For this reason, Xanax is prescribed for a short period of time, while Clonazepam as part of therapy can be taken for quite a long time. Given that Xanax is more rapidly eliminated from the body, side effects are observed within 2-4 hours. Clonazepam side effects may be present for several days.
Fatigue can be a side effect of taking Clonazepam. In this case, you should reduce the dosage or stop taking the drug.
However, withdrawal syndrome occurs when the dosage is reduced or Clonazepam is stopped suddenly. This condition carries a health risk. The risk of the syndrome occurs either by increasing the recommended dose or by prolonged use of the drug.
Before reducing the dosage or discontinuing it, you should see your doctor and strictly follow his or her recommendations.
Signs of overdose and intoxication differ depending on the individual reaction to the components of the remedy, weight, and age.
Most adults complain about the appearance of dysarthria (speech disorder, disorder of functioning of vocal cords, facial and respiratory muscles), ataxia (a motor disorder characterized by impaired coordination of movements of various muscles), and nystagmus (uncontrolled rhythmic movements of the eyeballs).
If the drug was taken as monotherapy, overdose carries a serious threat to health. Against this background, symptoms of aphlexia (choking), hypotension (severe decrease in blood pressure), or cardiorespiratory depression occur.
In the elderly, there is a risk of coma, which lasts from a few hours to a few days. Individuals with severe chronic obstructive airway disease show signs of respiratory depression. Clonazepam may also potentiate the effects of other drugs that have a CNS depressant effect.
Treatment of overdose involves gastric lavage and use of drugs that regulate the heart and CNS function.
There is a possibility of weight gain while taking Clonazepam, but it’s low. More often the opposite effect is observed: weight loss rather than weight gain.
According to clinical studies, weight gain while using this drug is observed in less than 1% of patients. It’s assumed that weight gain is a side effect of the product.
Unlike Clonazepam, Ativan is an anxiolytic. It’s taken intravenously, intramuscularly, and sublingually. It’s a short-acting benzodiazepine with a half-life of 15 hours.
Clonazepam is used to treat akinetic seizures as well as myoclonus. Alprazolam is used to treat acute panic attacks and anxiety disorders. The difference in the effects of the two medications is due to the difference in their chemical structure and composition.
The average dosage of Alprazolam (particularly for panic attacks) is 0.5 mg, 3 times/24 h. Clonazepam is prescribed in a lower dosage (the starting dose of this medication is 0.25 mg) and requires less intensive administration (no more than 2 times/24 hours).
The anticonvulsant effect is realized because presynaptic inhibition is enhanced when Clonazepam is taken. Epileptogenic activity is suppressed. But there is no removal of the excited state of the epileptogenic focus.
Clonazepam (Mexico) promotes rapid suppression of the paroxysmal activity of various types - in particular, "spikes" and "spike waves". The drug has the most beneficial effect on the body against the background of the development of a focal or generalized form of epilepsy.
Clonazepam and Valium (Diazepam) are commonly prescribed in the treatment of anxiety disorders. Diazepam is also used as part of the therapy of some neurological pathologies (in the presence of convulsive muscle contractions, delirium, tremor, and other similar symptoms). Diazepam is allowed for the treatment of hallucinations that occur against the background of withdrawal of alcohol-containing products.
Clonazepam is prescribed for certain types of seizures, such as akinetic seizures. It’s acceptable to use this medication when signs of Lennox-Gasto syndrome appear.
Diazepam is available not only in tablets, but also in the form of rectal gel, injections, and solutions for intravenous/intramuscular administration.
Melatonin is a synthetic analog of the epiphysis hormone (pineal body) melatonin. It’s intended to normalize circadian rhythms. The main effects are sedative and adaptogenic.
Against the background of taking this drug, there is an increase in the concentration of GABA in the hypothalamus and midbrain. The activity of pyridoxal kinase, which is involved in the synthesis of dopamine and serotonin, changes. Melatonin enhances the effect (reciprocally) of CNS depressant drugs and beta-adrenoblockers.
Decreased blood pressure is a side effect of Clonazepam. Additionally (especially in elderly patients) symptoms of tachycardia develop.
It’s not recommended to take Clonazepam during pregnancy because the active ingredients of the drug penetrate the placental barrier. This drug should not be taken during lactation either: Clonazepam is excreted with breast milk.
The drug may be prescribed to the future mother only if the therapeutic benefits significantly exceed the possible risks to the child. In the presence of severe seizures, the use of Clonazepam during the period of pregnancy should be under the supervision of a physician. In late pregnancy, the drug is not prescribed: otherwise, there is a risk of withdrawal effects in the child. These symptoms can be observed for several months.
Addiction to Clonazepam develops with prolonged use of this drug. With abrupt discontinuation, a "withdrawal syndrome" develops. Most patients complain of spontaneous but severe headaches. Some patients develop myalgia (muscle pains of various nature and localization).
Anxiety develops, which is accompanied by tension. Sometimes panic attacks are observed. The person becomes irritable, and at the same time, he/she has memory lapses accompanied by a decrease in concentration.
In the most severe cases, derealization develops - a severe condition characterized by impaired perception. The person perceives the world around him or her as unreal or distant. Depersonalization is also possible - a psychopathological symptom characterized by a disorder of self-perception of the personality.
Sometimes there is the development of hyperacusis - hearing impairment, which is characterized by increased sensitivity to certain frequencies and ranges of sound volume. Paresthesias may be observed in the extremities. Sometimes patients complain of tactile or light hypersensitivity.
Clonazepam has an effect on sleep. When taking this drug, sleep becomes deeper and more restful: nocturnal awakenings stop. The quality of sleep improves: the drug allows you to sleep better. The duration of sleep may not change.
In our pharma store, you can buy Clonazepam online at a favorable price. The prices of medicines in Mexico will allow you to purchase the necessary drugs without affecting the family budget.
To buy Clonazepam online, fill out the application form on the website. Clonazepam is delivered throughout Mexico and the United States.
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We offer Mex Post Express Shipping as an option. This option costs from $24.95 depending on the quantity of medications in your order (up to 9 medications). This option requires a customer signature on delivery. For all other locations Express Shipping is $39.95. All packages are shipped in plain packaging to guarantee your privacy. All packages are sent by parcel express mail from Mexico. Some parcels require a signature upon delivery at our discretion. There are no other handling fees, drug dispensing fees, or Mexican customs charges. If two or more people are ordering their prescription drugs from the same address at the same time, you will be billed for only one shipping charge from our Mexico pharmacy, up to our maximum order quantities limited by customs to 90 day supply. We are able to provide a tracking number on your express shipping parcels. If after 30 business days your order has not arrived, first check with your local postal office to ensure that your package is not being held for pick-up. If you still have problems, please contact us by email and we will attempt to assist you.
If no one is at home at the time of delivery, the status of you order on the Postal System will be updated to “Notice Left” which means USPS attempted to deliver your item and a notice was left because an authorized recipient was not available. You may arrange redelivery by visiting or calling 800-ASK-USPS, or may pick up the item at the Post Office indicated on the notice. If this item is unclaimed after five days then it will be returned to the sender. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).
Note that on Holidays season, the Mexican Postal, USA and other countries will be extra busy; therefore a delay is expected in packages shipped during this season. You will need to consider as well the Mexican holidays. We appreciate your understanding, our customer service will be happy to assist you and available to inform you the latest status on your existing order shipped, you can always contact us at Toll Free number or email address.
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How to find the online pharmacy drug you need.
There are many more medications available in Mexico that are not listed on our website. If you can’t find the Mexican drug or medication you require, please contact us and we may be able to help. Some products are listed only in a single dosage size or medicine type, but may be available in other dosages and forms. Our experienced Mexican pharmacy Pharmacists will do their best to accommodate your requirements. Please always specify the chemical name of the medication (and any applicable brand name) with all inquiries. Please feel free to ask about ANY drug. We will reply promptly to your request.
What you should know about brand and generic drug alternates.
Prescription drugs are a costly medical expense, especially for the elderly, those who are chronically ill and those with no or minimal drug coverage on their Health Insurance. However, each state in America has a law that allows pharmacists to substitute less expensive generic drugs for many brand name products. Depending on your prescription needs, your savings could be very significant. Before you talk with your doctor or pharmacist about switching, there are things you should know about generic drugs.
What is the difference between a generic and brand name drug?
Nothing except for the name, packaging, and the price, a generic drug is called by its chemical name; manufacturers assign their own brand name. The generic products have the same ingredients. Standard practice and most state laws require that a generic drug be generically equivalent to its brand name counterpart. That is, it must have the same active ingredients, strength, and dosage form, be it a pill, liquid, or injection. The generic drug also must be therapeutically equivalent. It must be the same drug chemically and have the same medical effect.
Do all drugs have generic equivalents?
No. Some drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.
Will my doctor automatically prescribe generic drugs?
It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate or to define the chemical name for the prescription. This will ensure you are purchasing the correct Mexico drug. Generic products will be as effective and less costly. Or, you can order only brand name products if you wish. www.mexicanrxpharm.com Mexico pharmacy offers a wide selection of both Brand Name & Generic Mexico medicine. Our Mexican generic drugs are of the highest quality, selected only from the most reputable manufacturers, and are safe to replace brand name medications costing much more.
Feel free to contact us for further information.
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