Stilnox is a sleeping pill that is used for the short-term treatment of various forms of insomnia, heavy drowsiness, restlessness, and short-term sleep in patients 18 years of age and older. Stilnox 10 mg does not require a prescription to purchase. Its main active ingredient is Zolpidem hemitartrate 10 mg in 1 tablet.
Short-term medication for:
The active ingredient has calming and stimulating effect on sleep by acting on special binding sites in the brain. Interaction with these binding sites enhances the effects of endogenous substances with relaxing and soporific effects.
The chemical active ingredient Zolpidem is a derivative of cyclopyrrolone. It interacts with the α and γ subunits of the GABA A receptor. This interaction with the GABA receptor results in enhanced GABA responses, which can be shown by electrophysiological techniques.
Stilnox Zolpidem gives these effects:
Compared with benzodiazepines, Z-substances have less effect on sleep architecture, particularly on the phases of REM sleep.
Zolpidem is rapidly absorbed and has a rapid sedative effect in less than an hour. Bioavailability after oral administration is 70 percent. Zolpidem exhibits linear kinetics between therapeutic doses. Therapeutic levels in plasma range from 80 to 200 ng/ml. Maximum saturation in the blood occurs between 30 and 180 minutes.
The effect lasts for about 6 hours. It is excreted with urine and feces for about 2.5 hours on average.
The CR form allows a sufficient amount of the drug to persist on the receptors. This improves overall sleep time and prevents early morning awakening, which may be associated with the immediate-release form of zolpidem.
Adults take one film-coated tablet of Stilnox per day. This dosage should not be exceeded.
Elderly or infirm patients only receive half a film-coated tablet per day. This dosage should only be exceeded in exceptional cases - then no more than one film-coated tablet can be taken per day!
Patients with impaired liver function should not take more than half a tablet a day.
It should be taken with a small amount of liquid just before going to bed. The treatment should last only a few days. However, it may last up to two weeks and in some cases may last more than four weeks.
Common side effects: drowsiness, sleepiness the next day, headache, suppression of emotions, decreased alertness, confusion, dizziness, gastrointestinal disturbances, diarrhea, nausea, vomiting, visual disturbances, double vision, skin reactions, and memory loss.
Common side effects: fatigue, muscle weakness, unsteady gait, and unsteady movements.
Rare side effects: decreased libido.
In addition, psychological and "paradoxical" reactions such as restlessness, agitation, irritability, disinhibition, aggressiveness, abnormal thinking, psychosis, unusual behavior, alien extraversion, and other behavioral problems may occur. These reactions are called "paradoxical" because they are opposite to the desired effects of sedation and drowsiness.
As the effects wear off, insomnia may occur with associated reactions such as restlessness, mood changes, or anxiety.
An already existing depressive state can manifest itself for the first time or worsen. Use can lead to the development of physical and mental dependence.
Current U.S. studies suggest that effective concentrations of Zolpidem are still present in the blood of some patients the next morning, even when following the instructions for use. This is particularly true in female patients because they are slower to break down the active ingredient.
Thus, your ability to respond may be reduced the morning after taking Zolpidem. Do not drive or engage in other activities that require full concentration for at least eight hours after taking Zolpidem.
Stilnox Zolpidem should not be taken if you are hypersensitive to zolpidem. In addition, contraindications include severe hepatic dysfunction, sleep apnea syndrome, progressive muscle weakness, myasthenia gravis and severe respiratory failure.
The following interactions should be considered when using Stilnox 10mg:
Alcohol: it is possible to increase the sedative effect of zolpidem, as well as the effect on the ability to drive vehicles and work with various mechanical devices.
In combination with other depressants, an increase in the central depressant effect is possible. Increased somnolence may be observed, and the following day - psychomotor disorders, including decreased ability to drive a car.
With antidepressants such as bupropion, desipramine, fluoxetine, sertraline, and venlafaxine, there may be a risk of visual deception.
Simultaneous use with narcotic analgesics may increase euphoria, which may accelerate the development of psychological dependence.
Although teratogenic or embryotoxic effects have not been demonstrated in animal studies, safety in pregnancy in humans has not been established. Therefore, zolpidem is not recommended, especially in the first three months of pregnancy. If zolpidem is administered for a medical emergency in late pregnancy or during delivery, effects on the newborn such as hypothermia, hypotension and mild respiratory depression are expected based on pharmacological properties.
Although Zolpidem penetrates breast milk in insignificant amounts, it is recommended to avoid taking it, since studies on the effect on infants have not been conducted.
Stilnox 10 mg buy online you can in our online pharmacy, and our qualified pharmacists will be able to advise on possible interactions.
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