Tramacet 37.5mg/325mg

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The combined analgesic agent Tramacet (Paracetamolum + Tramadolum) for the somatic treatment of severe pain syndrome. Tramacet is a thickening medication for oral use.

In the practice of an outpatient doctor, pain is one of the most frequent pathological symptoms for which a patient seeks a doctor. Pain can be a manifestation of a wide variety of diseases, including those related to the areas of special sections of medicine (surgery, oncology, neurology, etc.).

Brand name: Tramacet

Generic name: Acetaminophen and Tramadol

Composition Tramacet:

Active substance

1 tablet

tramadol hydrochloride

37.5 mg


325 mg


Excipients: microcrystalline cellulose, pregelatinized starch, sodium starch glycolate, corn starch, purified water, magnesium stearate.

Medical advice: be sure to consult with a specialist before using the medication. Self-use can harm your health.

Buy Tramacet Mexico online in our online pharmacy at market price, shipping worldwide.

Pharmaco-therapeutic group: analgesic agent with a mixed mechanism of action; analgesic non-narcotic agent.

Tramadol is an opioid synthetic analgesic, has an analgesic effect, is an agonist of opioid receptors. It has a central effect and action on the spinal cord (inhibits the conduct of pain impulses), enhances the effect of sedatives.

Paracetamol has analgesic and antipyretic effects. Blocks cyclooxygenase mainly in the central nervous system, affecting the centers of pain and thermoregulation. It does not irritate the gastrointestinal tract mucosa, does not affect water-salt metabolism.

Thus, both components of Tramacet have an inhibitory effect on different links in the conduction of pain impulses in the structures of the central nervous system, providing a synergistic analgesic effect. This synergy was the basis for determining the optimal ratio of reduced doses of tramadol and paracetamol acetaminophen when creating a finished combined dosage form: 37.5 / 325 mg.

You can order Tramacet Mexico in our online Mexican pharmacy with fast US delivery.


Indication Tramacet 37.5 mg

Always take this medication exactly as directed in the package insert, or as directed by your doctor or pharmacist. If you are unsure, check with your doctor or pharmacist.

For outpatient practice, acute and chronic severe pain syndromes of moderate intensity that are not relieved by simple non-opioid analgesics are most relevant, since they are especially common and cause difficulties for doctors in choosing an effective and affordable therapy. These include pain syndromes associated with diseases of the spine, joints, especially during periods of exacerbation, trauma, ambulatory invasive interventions.

You can buy the medicine in the USA at our Mexican online pharmacy. The medicine is dispensed without a prescription.


Contraindications Tramacet Mexico tablets

Unfortunately, even if there are indications for the use of the drug, it is not always used. You cannot use the drug if you are allergic (hypersensitive) to any of the ingredients or other benzodiazepines.

Before using Tramacet 37.5 mg tabs, familiarize yourself in detail with all possible contraindications:

- hypersensitivity to active or auxiliary components of the medicament;

- conditions accompanied by respiratory depression or severe depression of the central nervous system (including acute intoxication with alcohol or drugs, hypnotics, narcotic analgesics and psychotropic drugs);

- simultaneous administration of MAO inhibitors (and within 2 weeks after their cancellation);

- severe hepatic and / or renal failure (creatinine clearance less than 10 ml / min);

- epilepsy, uncontrolled by therapy;

- drug withdrawal symptoms;

- children up to age 14;

- pregnancy, lactation.


The drug Tramacet is prescribed with caution for the following diseases and conditions:

- traumatic brain injury, intracranial hypertension;

- a tendency to convulsive syndrome (in patients with therapeutically controlled epilepsy, the drug can only be used for health reasons);

- shock, confusion of consciousness of unknown etiology, impaired respiratory function;

- with the simultaneous use of psychotropic and other pain relievers of central action, local anesthesia;

- before general anesthesia;

- diseases of the biliary tract; benign hyperbilirubinemia, viral hepatitis, glucose-6-phosphate dehydrogenase deficiency;

- alcoholic liver damage, alcoholism, drug addiction;

- hepatic and renal (creatinine clearance less than 10-30 ml / min) failure of moderate severity;

- against the background of pain in the abdominal cavity of unknown origin ("acute abdomen");

- elderly patients (over 75 years old).

FDA Recommendations - Category C. Contraindicated in pregnancy and lactation.


Dosage and method of administration Tramacet

Take your medication exactly as directed by your treating psychotherapist.

Do not take Tramacet or its analogues without a doctor's prescription, remember that self-medication can worsen your condition and harm your brain and overall health. The dosage regimen and duration of treatment are selected individually depending on the severity of the pain syndrome.

Inside, 1-2 tablets for pain, the interval in admission is at least 6 hours.

Highest daily dose: 8 tablets (2.6 paracetamol acetaminophen and 300 mg of tramadolum).

Higher single dose: 2 tablets.

You can buy Tramacet tablets pain relief (Acetaminophen + Tramadol 37.5 / 325 Mg) in the USA from our online pharmacy at market prices. Delivery throughout the country.


Overdosage of Tramacet Mexico

Acetaminophen: diarrhea, anorexia - with acute overdose (develops 6-14 hours after exceeding the dose), with chronic (develops 2-4 days after exceeding the dose) - hypocoagulation, disseminated intravascular coagulation syndrome, cerebral edema, rarely - fulminant renal failure due to tubular necrosis.

Tramadol hydrochloride: miosis, collapse, coma, convulsions, apnea.

Necrosis of liver cells due to the formation of a toxic metabolite of acetaminophen - N-acetyl-p-benzoquinone imine.

Treatment: the use of donors of SH-groups, precursors of the synthesis of glutathione - methionine and N-acetylcysteine ​​within 12 hours after an overdose.

Introduction of naloxone, diazepam.


Side effects of Tramacet 37.5 mg tabs

If you find any of the adverse reactions, discontinue treatment and immediately go to the hospital. In this case, the doctor is obliged to recommend another treatment.

Possible side reactions in patients.

System and organs

Side effects

Respiratory system


Hematopoietic system

sulfhemoglobinemia, aplastic anemia, pancytopenia

The cardiovascular system

tachycardia, orthostatic hypotension, syncope

Digestive system

dry mouth, nausea, vomiting, flatulence, constipation, difficulty swallowing, diarrhea.

Central and peripheral nervous system

dizziness, headache, lethargy, nervousness, euphoria, hallucinations, tremors, muscle spasms, impaired cognitive function, gait instability, paresthesias, visual and taste disturbances

Endocrine system


Reproductive system

violation of the menstrual cycle

Dermatological reactions

hyperhidrosis, bullous rash, toxic epidermal necrolysis (Lyell's syndrome)

The immune system

allergic reactions

Check with your pharmacist for full information on adverse reactions.

Buy Tramacet online easily over the counter!


Special instructions

One in two or three people who develop cancer experience pain that is moderate to severe. The pain tends to get worse as the cancer progresses.

Monitoring of plasma glucose and uric acid, peripheral blood composition, liver functional state.

With prolonged use of the medicament, symptoms of drug dependence develop, with a sudden discontinuation of the drug - withdrawal syndrome.

During the period of treatment, alcohol is prohibited.

During treatment, driving a car and working with moving mechanisms is not recommended.

You can buy tramacet in the USA without a prescription from our online Mexican pharmacy


What is tramacet?

Tramacet is a combination pain reliever consisting of 37.5 mg tramadol hydrochloride and 325 mg acetaminophen. The medicine is used to relieve severe pain syndromes, regardless of genesis.


Which is better for pain tramadol or tramacet?

Tramacet is more effective than tramadol. Paracetamol acetaminophen accelerates the onset of the analgesic effect, tramadol prolongs it. The combination of tramadol + paracetamol was more effective; the effect was faster and lasted longer than the component of the remedy alone.


Para que sirve?

El agente analgésico combinado Tramacet (Acetaminophen + Tramadolum) para el tratamiento somático del síndrome de dolor. Tramacet México es un analgésico oral. El medicamento se prescribe para los síndromes de dolor agudo y crónico de intensidad moderada que no pueden detenerse con analgésicos simples no opioides.


TRAMACET tablets are indicated for the symptomatic treatment of moderate to severe pain. Tramacet may also be used for purposes other than those listed in this medication guide. Please consult your physician before taking any medication.


What is the difference between Tramacet and Celebrex

Tramacet is prescribed for the symptomatic treatment of moderate to severe pain. The origin of the pain may be:

  • vascular;

  • traumatic;

  • inflammatory.

It may also be used for pain relief during diagnostic or therapeutic procedures.

Celebrex is good for the symptomatic treatment of joint pathologies and primary dysmenorrhea.

Which drug is more effective: Tramacet or Celebrex

Tramacet 37.5 is more effective in that the analgesic effect comes on faster. 

What is the half-life of Tramacet

The half-life of Tramacet tablet:

  • paracetamol - 120-180 minutes;

  • Tramacetol - 4.6-5.1 h.

In people with renal insufficiency, the half-life is longer.

Comparison of Demerol and Tramacet

Demerol (another name is Meperidine) is an opioid painkiller that can be used to treat severe pain in certain cases. Sometimes Demerol is used instead of Morphine.

The difference between the drugs is the effect on the respiratory system: Demerol depresses it. 

What is the difference between Tramadol and Tramacet

Tramadol apap 37.5mg 325mg Tramacet is available in tablets. Tramadol is available as a solution for injection.

Which is better for pain, Tramadol or Tramacet

Tramadol helps with moderate to severe pain. This medication is mostly used in the post-operative period, as well as to treat pain in cancer patients.
Tramacet medicament is more effective than "pure" Tramadol. This medication contains Paracetamol, which accelerates the onset of pain relief. Tramadol, which is also in the composition, prolongs it.

Reviews Tramacet 37.5mg/325mg

Excellent service. They keep you up to date every step of the process.
Good strong pill. Exactly as described. Expect shipping from Mexico to take a little longer than you are used to with customs in 2 countries involved. Great service

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Shipping & Returns

 we are a Registered and Licensed Mexican pharmacy we assure you top quality medicines without the worry of your health care provider, employer or any other group finding out what rightfully is a private issue.

Did you know that your private medical file can be used against you to raise your insurance rates or in some cases and countries to lose your job? We take your privacy very seriously and by using these payment methods and the way in which we use them your bank does not directly get charged from our pharmacy. This way your medical needs stay as private as possible.

You will also receive a complete invoice in your email with payment totals and simple payment instructions toward the bottom of the email should you wish to pay at a later convenience.

IMPORTANT: If you need to make some changes in regards an existing order, contact us within 24 hours, otherwise, Medicines Mexico is not liable due to errors on customer’s information or products presentation. 


Shipping Methods.

To ensure the delivery of your order we handle EXPRESS SHIPPING only. Signature is required.
Tracking numbers for all orders will be sent with instructions once shipped.


How long does it take to ship the drugs to my home or office?

  • Express USA time frame: 10-21 business days.   ($24.95 USD Signature required)
  • Express World Wide time frame: 15-30 business days.  ($39.95 USD Signature required)


*Due to unexpected Postal Service changes, one of the shipping methods above could be temporarily disabled.

IMPORTANT: Please ensure your mail program is configured to accept email from sender, add our email to your non blocked email address so we may send invoices, order status and shipping confirmations. If you do not receive your invoice immediately after this, please check your spam filter and make necessary changes. 

We reply promptly to your enquiries and requests emails, but are too busy to repeatedly resend email that customers do not receive because our replies have been moved to a customers’ Spam, Junk or Bulk email folder.

Online pharmacy Medicines Mexico shipping terms and conditions.
Our team endeavors to process all orders and ship within 72 business hours. All credit card and electronic check payments for your mexicanrxpharm take 24 to 48 hours to be approved by our Payment Processor; upon verification your order will be processed. If there are any problems with your order, we will contact you, so please ensure the email address and phone number you provide is correct, and that any spam filtering software you use accepts email from

Express Shipping.
We offer Mex Post Express Shipping as an option. This option costs from $24.95 depending on the quantity of medications in your order (up to 9 medications). This option requires a customer signature on delivery. For all other locations Express Shipping is $39.95. All packages are shipped in plain packaging to guarantee your privacy. All packages are sent by parcel express mail from Mexico. Some parcels require a signature upon delivery at our discretion. There are no other handling fees, drug dispensing fees, or Mexican customs charges. If two or more people are ordering their prescription drugs from the same address at the same time, you will be billed for only one shipping charge from our Mexico pharmacy, up to our maximum order quantities limited by customs to 90 day supply. We are able to provide a tracking number on your express shipping parcels. If after 30 business days your order has not arrived, first check with your local postal office to ensure that your package is not being held for pick-up. If you still have problems, please contact us by email and we will attempt to assist you.

Notice Left
If no one is at home at the time of delivery, the status of you order on the Postal System will be updated to “Notice Left” which means USPS attempted to deliver your item and a notice was left because an authorized recipient was not available. You may arrange redelivery by visiting or calling 800-ASK-USPS, or may pick up the item at the Post Office indicated on the notice. If this item is unclaimed after five days then it will be returned to the sender. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).

Note that on Holidays season, the Mexican Postal, USA and other countries will be extra busy; therefore a delay is expected in packages shipped during this season. You will need to consider as well the Mexican holidays. We appreciate your understanding, our customer service will be happy to assist you and available to inform you the latest status on your existing order shipped, you can always contact us at Toll Free number or email address.

Order Cancellation
Due to our policy of same day payment processing, ORDERS CANNOT BE CANCELLED.

Due to government regulations and the possibility of tampering with medications, returns cannot be accepted. In case your package is returned due to no one was available to sign for it. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).

How to find the online pharmacy drug you need.
There are many more medications available in Mexico that are not listed on our website. If you can’t find the Mexican drug or medication you require, please contact us and we may be able to help. Some products are listed only in a single dosage size or medicine type, but may be available in other dosages and forms. Our experienced Mexican pharmacy Pharmacists will do their best to accommodate your requirements. Please always specify the chemical name of the medication (and any applicable brand name) with all inquiries. Please feel free to ask about ANY drug. We will reply promptly to your request.

What you should know about brand and generic drug alternates.
Prescription drugs are a costly medical expense, especially for the elderly, those who are chronically ill and those with no or minimal drug coverage on their Health Insurance. However, each state in America has a law that allows pharmacists to substitute less expensive generic drugs for many brand name products. Depending on your prescription needs, your savings could be very significant. Before you talk with your doctor or pharmacist about switching, there are things you should know about generic drugs.

What is the difference between a generic and brand name drug?
Nothing except for the name, packaging, and the price, a generic drug is called by its chemical name; manufacturers assign their own brand name. The generic products have the same ingredients. Standard practice and most state laws require that a generic drug be generically equivalent to its brand name counterpart. That is, it must have the same active ingredients, strength, and dosage form, be it a pill, liquid, or injection. The generic drug also must be therapeutically equivalent. It must be the same drug chemically and have the same medical effect.

Do all drugs have generic equivalents?
No. Some drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.

Will my doctor automatically prescribe generic drugs?
It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate or to define the chemical name for the prescription. This will ensure you are purchasing the correct Mexico drug. Generic products will be as effective and less costly. Or, you can order only brand name products if you wish. Mexico pharmacy offers a wide selection of both Brand Name & Generic Mexico medicine. Our Mexican generic drugs are of the highest quality, selected only from the most reputable manufacturers, and are safe to replace brand name medications costing much more.



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Tramacet 37.5mg/325mg
In stock


Tramacet 37.5mg/325mg