Temgesic Sublingual Bupremorphine 0.2 mg 10 Tabs

Out of stock
$127.37

 

Buprenorphine (tablets) is an opioid analgesic with low addictive potential. It is a partial agonist of μ-receptors and an antagonist (to some extent) of κ-receptors. The effectiveness of the drug is slightly inferior to morphine.

Buprenorphine: mechanism of action

Administration of Buprenorphine (tablets) promotes disruption of conduction of pain impulses in afferent pathways of CNS. Against the background of stimulation of postsynaptic opioid receptors, there is inhibition of activation of insertion neurons (this occurs under the influence of the mediator) and disruption of the depolarization process of the postsynaptic membrane. 

Also, administration of Buprenorphine (tablets) is associated with the strengthening inhibitory effects of descending antinociceptive system on pain impulses in the CNS (more precisely - in its afferent pathways). 

Taking Buprenorphine (tablets) contributes to the change of emotional coloring of pain syndrome. The reaction to it also changes. As a result, the transmission of pain impulses is disrupted at the level of the spinal cord. 

Buprenorphine: half-life 

The active ingredient is eliminated from plasma within 2-4 hours. Complete elimination of the 1st dose sometimes takes up to 6 days. Its detection time in urine is about 36 hours. 

Buprenorphine: dosage for pain

The drug is administered by injection and sublingually (under the tongue). When injected intramuscularly and intravenously, the dosage is 0.3-0.45 mg. If the pain is severe, injections are given every 6-8 hours.

Buprenorphine (tablet) is taken at a dose of 0.2-0.4 mg. Buprenorphine (0.2 mg) is the minimum dose. In severe pain, it may be increased to a maximum of 1.8 mg.

Buprenorphine: dosage

The dosage of Buprenorphine (tablet) increases gradually, depending on the clinical effect. The average daily maintenance dose is 8 mg. 

The dose is titrated according to the severity of the clinical condition. If stabilization is not achieved on a dosage of 8-16 mg/24 h, it is attributed to inappropriate administration of the drug. In such cases, alternative treatment options are considered.

Once satisfactory stabilization is achieved, the dose of Buprenorphine (tablet) may be reduced. If the physician determines it is appropriate, treatment is discontinued.

Buprenorphine and alcohol

It is not recommended that Buprenorphine tablets be taken at the same time as alcohol-containing products. Otherwise, the depressing effect on the CNS is intensified. This can have a particularly strong effect on the respiratory center. 

Side effects of buprenorphine

Buprenorphine pills may cause an allergic reaction. This is mostly manifested by facial hyperemia. Sometimes a characteristic (vesicular) rash appears on the face, accompanied by excruciating itching. After taking an antihistamine drug, the unpleasant symptom disappears.
Less frequently, taking this drug provokes the development of Quincke's edema. This condition is accompanied by swelling of the face and trachea and laryngospasm (sharp involuntary contraction of the muscles of the larynx, leading to complete closure of the vocal slit). There may be some swelling or burning at the injection area.

Some people complain of problems with their respiratory system:
 

  • Bronchospasm (narrowing of the lumen of the small branches of the bronchial tree);
  • Respiratory center depression (a pathology in which the normal blood gas composition is not maintained)
  • Atelectasis (loss of airiness of a part of the lung, occurring acutely or over a long period of time).

Against the background of taking the medicine, a person may feel nauseous and vomit. Sometimes this condition is combined with loose stools and dry mouth. Some people complain of excruciating stomach cramps. 

Individuals over 50 years of age report sharp spikes in blood pressure and tachycardia/bradycardia. 

Younger patients present with complaints of nervous system abnormalities. They complain of weakness (increased toward the end of the day), drowsiness (present throughout the day), and dizziness. Some have impaired coordination of movements. 

There is an increase in IOP (with the possibility of impaired circulation in the brain). Depersonalization and hallucinosis are sometimes observed. 

Against the background of high doses, CNS is depressed, and stiffness of respiratory muscles is observed.

Buprenorphine: Interactions

Caution should be exercised when combining Buprenorphine pill with:

  • Sedatives (particularly benzodiazepines). Adverse reactions: sedation, respiratory depression, coma, and death. Caused by additive CNS depressant effects
  • Opioid analgesics. When taking them simultaneously with the Buprenorphine pill, patients may have difficulty achieving sufficient analgesia. There is also a high risk of overdose
  • Naltrexone. This drug is an opioid receptor antagonist. It can block the pharmacological effects of Buprenorphine
  • Gabapentinoids. Against the background of respiratory depression, this combination can be lethal.

You can inexpensively buy Buprenorphine online on site. Just fill out an application form and provide your name and address. The order is delivered all over Mexico and the USA.

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These are the payment methods available:

  • Money Transfer ( Money Gram or Western Union)
  • Bitcoin
  • Paypal
  • Bank Wire

 

Shipping & Returns

 we are a Registered and Licensed Mexican pharmacy we assure you top quality medicines without the worry of your health care provider, employer or any other group finding out what rightfully is a private issue.

Did you know that your private medical file can be used against you to raise your insurance rates or in some cases and countries to lose your job? We take your privacy very seriously and by using these payment methods and the way in which we use them your bank does not directly get charged from our pharmacy. This way your medical needs stay as private as possible.

You will also receive a complete invoice in your email with payment totals and simple payment instructions toward the bottom of the email should you wish to pay at a later convenience.

IMPORTANT: If you need to make some changes in regards an existing order, contact us within 24 hours, otherwise, Medicines Mexico is not liable due to errors on customer’s information or products presentation. 

 

Shipping Methods.

To ensure the delivery of your order we handle EXPRESS SHIPPING only. Signature is required.
Tracking numbers for all orders will be sent with instructions once shipped.

 

How long does it take to ship the drugs to my home or office?

  • Express USA time frame: 10-21 business days.   ($24.95 USD Signature required)
  • Express World Wide time frame: 15-30 business days.  ($39.95 USD Signature required)

 

*Due to unexpected Postal Service changes, one of the shipping methods above could be temporarily disabled.
 

IMPORTANT: Please ensure your mail program is configured to accept email from www.mexicanrxpharm.com sender, add our email to your non blocked email address so we may send invoices, order status and shipping confirmations. If you do not receive your invoice immediately after this, please check your spam filter and make necessary changes. 

We reply promptly to your enquiries and requests emails, but are too busy to repeatedly resend email that customers do not receive because our replies have been moved to a customers’ Spam, Junk or Bulk email folder.

Online pharmacy Medicines Mexico shipping terms and conditions.
Our team endeavors to process all orders and ship within 72 business hours. All credit card and electronic check payments for your mexicanrxpharm take 24 to 48 hours to be approved by our Payment Processor; upon verification your order will be processed. If there are any problems with your order, we will contact you, so please ensure the email address and phone number you provide is correct, and that any spam filtering software you use accepts email from www.mexicanrxpharm.com

Express Shipping.
We offer Mex Post Express Shipping as an option. This option costs from $24.95 depending on the quantity of medications in your order (up to 9 medications). This option requires a customer signature on delivery. For all other locations Express Shipping is $39.95. All packages are shipped in plain packaging to guarantee your privacy. All packages are sent by parcel express mail from Mexico. Some parcels require a signature upon delivery at our discretion. There are no other handling fees, drug dispensing fees, or Mexican customs charges. If two or more people are ordering their prescription drugs from the same address at the same time, you will be billed for only one shipping charge from our Mexico pharmacy, up to our maximum order quantities limited by customs to 90 day supply. We are able to provide a tracking number on your express shipping parcels. If after 30 business days your order has not arrived, first check with your local postal office to ensure that your package is not being held for pick-up. If you still have problems, please contact us by email and we will attempt to assist you.

Notice Left
If no one is at home at the time of delivery, the status of you order on the Postal System will be updated to “Notice Left” which means USPS attempted to deliver your item and a notice was left because an authorized recipient was not available. You may arrange redelivery by visiting or calling 800-ASK-USPS, or may pick up the item at the Post Office indicated on the notice. If this item is unclaimed after five days then it will be returned to the sender. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).

Holidays
Note that on Holidays season, the Mexican Postal, USA and other countries will be extra busy; therefore a delay is expected in packages shipped during this season. You will need to consider as well the Mexican holidays. We appreciate your understanding, our customer service will be happy to assist you and available to inform you the latest status on your existing order shipped, you can always contact us at Toll Free number or email address.

Order Cancellation
Due to our policy of same day payment processing, ORDERS CANNOT BE CANCELLED.

Returns
Due to government regulations and the possibility of tampering with medications, returns cannot be accepted. In case your package is returned due to no one was available to sign for it. You can pay for reshipping $24.95 in order to receive a new tracking number. (Reshipping will be issued until the package is received back in our offices).

How to find the online pharmacy drug you need.
There are many more medications available in Mexico that are not listed on our website. If you can’t find the Mexican drug or medication you require, please contact us and we may be able to help. Some products are listed only in a single dosage size or medicine type, but may be available in other dosages and forms. Our experienced Mexican pharmacy Pharmacists will do their best to accommodate your requirements. Please always specify the chemical name of the medication (and any applicable brand name) with all inquiries. Please feel free to ask about ANY drug. We will reply promptly to your request.

What you should know about brand and generic drug alternates.
Prescription drugs are a costly medical expense, especially for the elderly, those who are chronically ill and those with no or minimal drug coverage on their Health Insurance. However, each state in America has a law that allows pharmacists to substitute less expensive generic drugs for many brand name products. Depending on your prescription needs, your savings could be very significant. Before you talk with your doctor or pharmacist about switching, there are things you should know about generic drugs.

What is the difference between a generic and brand name drug?
Nothing except for the name, packaging, and the price, a generic drug is called by its chemical name; manufacturers assign their own brand name. The generic products have the same ingredients. Standard practice and most state laws require that a generic drug be generically equivalent to its brand name counterpart. That is, it must have the same active ingredients, strength, and dosage form, be it a pill, liquid, or injection. The generic drug also must be therapeutically equivalent. It must be the same drug chemically and have the same medical effect.

Do all drugs have generic equivalents?
No. Some drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.

Will my doctor automatically prescribe generic drugs?
It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate or to define the chemical name for the prescription. This will ensure you are purchasing the correct Mexico drug. Generic products will be as effective and less costly. Or, you can order only brand name products if you wish. www.mexicanrxpharm.com Mexico pharmacy offers a wide selection of both Brand Name & Generic Mexico medicine. Our Mexican generic drugs are of the highest quality, selected only from the most reputable manufacturers, and are safe to replace brand name medications costing much more.

 


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